GNE-6640

  • Chemical Properties
CAS No. 2009273-67-8 Cat. No. BCP31358
Name GNE-6640
Synonyms GNE 6640; GNE6640;
Formula C20H18N4O M. Wt 330.38
  • Biological Activity
Description GNE-6640 is a selective and non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM, 0.43 μM, 20.3 μM and 0.23 μM for full length USP7, USP7 catalytic domain, full length USP43 and Ub-MDM2, respectively.
Pathways Cell Cycle/DNA Damage 
Targets DUB 

Structure

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