Xanomeline tartrate
| CAS号 | 152854-19-8 | 货号 | BCP31493 |
| 中文名 | Xanomeline tartrate | ||
| 英文名 | Xanomeline tartrate | ||
| 中文别名 | |||
| 英文别名 | LY 246708 tartrate;LY246708 tartrate;LY-246708 tartrate; | ||
| 分子式 | C18H29N3O7S | 分子量 | 431.50 |
| 生物活性 | Xanomeline s a muscarinic acetylcholine receptor agonist with reasonable selectivity for the M1 and M4 subtypes, though it is also known to act as a M5 receptor antagonist. It has been studied for the treatment of both Alzheimer's disease and schizophrenia, particularly the cognitive and negative symptoms, although gastrointestinal side effects led to a high drop-out rate in clinical trials. Despite this, xanomeline has been shown to have reasonable efficacy for the treatment of schizophrenia symptoms, and one recent human study found robust improvements in verbal learning and short-term memory associated with xanomeline treatment. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | mAChR | ||
结构式
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