BOS-172722

  • Chemical Properties
CAS No. 1578245-44-9 Cat. No. BCP31542
Name BOS-172722
Synonyms BOS172722; BOS 172722;
Formula C24H30N8O M. Wt 446.55
  • Biological Activity
Description BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication. The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects.
Pathways Cell Cycle/DNA Damage 
Targets Mps1 

Structure

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