BOS-172722
| CAS号 | 1578245-44-9 | 货号 | BCP31542 |
| 中文名 | BOS-172722 | ||
| 英文名 | BOS-172722 | ||
| 中文别名 | |||
| 英文别名 | BOS172722; BOS 172722; | ||
| 分子式 | C24H30N8O | 分子量 | 446.55 |
| 生物活性 | BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication. The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects. | ||
| 信号通路 | Cell Cycle/DNA Damage | ||
| 靶 点 | Mps1 | ||
结构式
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