Banoxantrone dihydrochloride
| CAS No. | 252979-56-9 | Cat. No. | BCP31589 |
| Name | Banoxantrone dihydrochloride | ||
| Synonyms | Banoxantrone 2HCl;AQ4N dihydrochloride; | ||
| Formula | C22H30Cl2N4O6 | M. Wt | 517.40 |
| Description | Banoxantrone dihydrochloride, a bioreductive prodrug, can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor, and exhibits little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM). | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Topoisomerase | ||
Structure
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