THIQ

  • Chemical Properties
CAS No. 312637-48-2 Cat. No. BCP31597
Name THIQ
Synonyms 3-IsoquinolinecarboxaMide,N-[(1R)-1-[(4-chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-,(3R)-;
Formula C33H41ClN6O2 M. Wt 589.18
  • Biological Activity
Description THIQ is a potent and selective melanocortin 4 (MC4) receptor agonist (IC50 values are 1.2, 761 and 2067 nM for human MC4, MC3 and MC1 receptors respectively). Enhances intracavernosal pressure and stimulates erectile activity in rats ex copula following systemic administration.
Pathways GPCR/G Protein 
Targets Melanocortin Receptor 

Structure

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