6-Mercaptopurine riboside

Chemical Properties

CAS No.	574-25-4	Cat. No.	BCP31879
Name	6-Mercaptopurine riboside
Synonyms	6TI;6-Thioinosine;Thioinosine;
Formula	C10H12N4O4S	M. Wt	284.29

Biological Activity

Description	Thioinosine is a sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de novo purine synthesis and perturbs the pool of nucleotides necessary for DNA replication. As a result, this agent inhibits DNA synthesis, blocks cellular proliferation and induces apoptosis.

Description

Thioinosine is a sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de novo purine synthesis and perturbs the pool of nucleotides necessary for DNA replication. As a result, this agent inhibits DNA synthesis, blocks cellular proliferation and induces apoptosis.

Structure

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