MOTS-c (human)
| CAS No. | 1627580-64-6 | Cat. No. | BCP31969 |
| Name | MOTS-c (human) | ||
| Synonyms | MOTS-C;H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH . TFA; Mitochondrial Open Reading Frame of the 12S rRNA-c; MOTS3; | ||
| Formula | C101H152N28O22S2 . C2HF3O2 | M. Wt | 2288.6 |
| Description | MOTS-c is a mitochondria-derived peptide (MDP) that promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK). Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice. Potential anti-obesity and anti-aging compound. | ||
| Pathways | PI3K/Akt/mTOR Epigenetics | ||
| Targets | AMPK | ||
Structure
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