PF-03463275 HCl
CAS No. | 1173177-11-1 | Cat. No. | BCP32015 |
Name | PF-03463275 HCl | ||
Synonyms | PF-03463275; PF03463275; PF 03463275; PF-3463275; PF3463275; PF 3463275; | ||
Formula | C19H23Cl2FN4O | M. Wt | 413.3 |
Description | PF-03463275 (PF 3463275) ia an orally bioavailable, centrally penetrant, potent, reversible, selective, and competitive inhibitor of the human GlyT1 transporter with Ki of 13 nM; shows no significant affinity for GlyT2 (Ki >1 mM); is under investigation for the treatment of schizophrenia. | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | GlyT |
Structure
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