SU 3327
| CAS No. | 40045-50-9 | Cat. No. | BCP32078 |
| Name | SU 3327 | ||
| Synonyms | SU3327; SU-3327; | ||
| Formula | C5H3N5O2S3 | M. Wt | 261.3 |
| Description | SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM). Inhibits the protein-protein interaction between JNK and JIP (IC50 = 239 nM). Displays selectivity over p38 MAPK and Akt. Restores insulin sensitivity in a mouse model of type-2 diabetes. Displays antibiotic activity against a range of bacteria including S.aureus, A.baumanni, C.difficile and M.tuberculosis. | ||
| Pathways | MAPK Pathway | ||
| Targets | JNK | ||
Structure
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