PF-5190457

  • Chemical Properties
CAS No. 1334782-79-4 Cat. No. BCP32122
Name PF-5190457
Synonyms PF 5190457; PF5190457; PF-05190457; PF05190457; PF 05190457;
Formula C29H32N6OS M. Wt 512.68
  • Biological Activity
Description PF-5190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-5190457 potently increases insulin secretion in glucose-stimulated human islets. PF-5190457 has a superior balance of ghrelin receptor pharmacology and off-target selectivity.
Pathways GPCR/G Protein 
Targets GHSR 

Structure

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