Monna
CAS No. | 1572936-83-4 | Cat. No. | BCP32415 |
Name | Monna | ||
Synonyms | 2-[(4-Methoxy-2-naphthalenyl)amino]-5-nitro-benzoic acid; | ||
Formula | C18H14N2O5 | M. Wt | 338.31 |
Description | MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 = 80 nM). Exhibits >100-fold selectivity for TMEM16A over bestrophin-1, CLC2 and CFTR. Induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions. | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | Chloride Channel |
Structure
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