iCRT3

  • Chemical Properties
CAS No. 901751-47-1 Cat. No. BCP32691
Name iCRT3
Synonyms iCRT-3;
Formula C23H26N2O2S M. Wt 394.53
  • Biological Activity
Description iCRT3 is an inhibitor of the Wnt/wingless signaling pathway. iCRT3 efficiently block Wnt/β-catenin-induced target genes and phenotypes in various mammalian and cancer cell lines. Importantly, these Wnt inhibitors are specifically cytotoxic to human colon tumor biopsy cultures as well as colon cancer cell lines that exhibit deregulated Wnt signaling.
Pathways Wnt/Stem Cell 
Targets Wnt 

Structure

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