Nelonicline

  • 化学数据
CAS号 1026134-63-3 货号 BCP32806
中文名 Nelonicline
英文名 Nelonicline
中文别名
英文别名 ABT-126; ABT126; ABT 126;
分子式 C17H19N3OS 分子量 313.42
  • 用途
生物活性 Nelonicline, aslo known as ABT-126, is an Alpha7 nicotinic acetylcholine receptor agonist and Nicotinic acetylcholine receptor agonist. Nelonicline is potentially useful for the treatment of Alzheimer's diseases. ABT-126 may be useful to reduce dyskinesias in both early- and later-stage Parkinson's disease. Accumulating evidence suggests that the α7 subtype of nicotinic acetylcholine receptors (nAChRs) plays a key role in inflammatory processes, thought to be involved in the pathophysiology of neuropsychiatric diseases, such as schizophrenia and Alzheimer's disease.
信号通路 Ion Channel/Membrane Transporter Neuro Signaling Pathway 
靶 点 nAChR 

结构式

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