Nelonicline
CAS号 | 1026134-63-3 | 货号 | BCP32806 |
中文名 | Nelonicline | ||
英文名 | Nelonicline | ||
中文别名 | |||
英文别名 | ABT-126; ABT126; ABT 126; | ||
分子式 | C17H19N3OS | 分子量 | 313.42 |
生物活性 | Nelonicline, aslo known as ABT-126, is an Alpha7 nicotinic acetylcholine receptor agonist and Nicotinic acetylcholine receptor agonist. Nelonicline is potentially useful for the treatment of Alzheimer's diseases. ABT-126 may be useful to reduce dyskinesias in both early- and later-stage Parkinson's disease. Accumulating evidence suggests that the α7 subtype of nicotinic acetylcholine receptors (nAChRs) plays a key role in inflammatory processes, thought to be involved in the pathophysiology of neuropsychiatric diseases, such as schizophrenia and Alzheimer's disease. | ||
信号通路 | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
靶 点 | nAChR |
结构式

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