AS601245
| CAS No. | 345987-15-7 | Cat. No. | BCP32871 |
| Name | AS601245 | ||
| Synonyms | AS-601245; AS 601245; | ||
| Formula | C20H16N6S | M. Wt | 372.45 |
| Description | AS601245 is a potent and selective JNK inhibitor. AS601245 decrease cell adhesion and migration through modulation of specific gene expression in human colon cancer cells. AS601245 and clofibrate have a synergistic effect in inducing cell responses and in affecting the cene expression profile in CaCo-2 colon cancer cells. AS601245 reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils. AS601245 shows promising neuroprotective properties. | ||
| Pathways | MAPK Pathway | ||
| Targets | JNK | ||
Structure
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