BMS-182874 Hydrochloride
| CAS No. | 1215703-04-0 | Cat. No. | BCP33050 |
| Name | BMS-182874 Hydrochloride | ||
| Synonyms | BMS 182874 HCl;BMS-182874 HCl; BMS182874 HCl; BMS-182874 hydrochloride; | ||
| Formula | C17H20ClN3O3S | M. Wt | 381.88 |
| Description | BMS 182874 hydrochloride is a potent, selective, and competitive non-peptide endothelin ETAR antagonist. It displays > 1000-fold selectivity over ETB receptors. BMS 182874 hydrochloride inhibits ET-1-induced pressor response in vivo. It inhibits ET-1-induced pressor response, and also inhibits ET-1-induced longitudinal muscle contraction in vitro. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Endothelin Receptor | ||
Structure
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