CGS 20625
| CAS No. | 111205-55-1 | Cat. No. | BCP33079 |
| Name | CGS 20625 | ||
| Synonyms | CGS20625;CGS-20625; | ||
| Formula | C18H19N3O2 | M. Wt | 309.36 |
| Description | CGS 20625 is a selective, partial agonist for the benzodiazepine binding site of the GABAA receptor. Potently inhibits [3H]-flunitrazepam binding to central benzodiazepine receptors (IC50 = 1.3 nM) and displays weak affinity for peripheral benzodiazepine (IC50 = 0.68 - 2.25 μM) and GABA binding sites (IC50 > 10000 μM). Displays anxiolytic activity in vivo following oral administration. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
| Targets | GABA Receptor | ||
Structure
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