洛索立宾
| CAS号 | 121288-39-9 | 货号 | BCP33260 |
| 中文名 | 洛索立宾 | ||
| 英文名 | Loxoribine | ||
| 中文别名 | 7-烯丙基-8-氧代鸟苷; | ||
| 英文别名 | 7-Allyl-8-oxoguanosine;Loxoribina; Loxoribinum; RWJ-21757; RWJ 21757; RWJ21757; | ||
| 分子式 | C13H17N5O6 | 分子量 | 339.31 |
| 生物活性 | Loxoribine is a guanine ribonucleotide derivative with immunostimulatory and immunomodulatory activity. Loxoribine undergoes facilitated transport across the plasma membrane into the cytoplasmic compartment of the cell and acts intracellularly, bypassing the biochemical steps involved in the membrane signal transduction pathway used by Ag or anti-IgM Abs to activate B cells. This agent activates the Toll-like receptor 7 (TLR7), a member of the TLR family of pathogen-associated molecular pattern recognition receptors thereby activating the innate immune system. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | TLR | ||
结构式
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