Decoglurant
| CAS号 | 911115-16-7 | 货号 | BCP33908 |
| 中文名 | Decoglurant | ||
| 英文名 | Decoglurant | ||
| 中文别名 | |||
| 英文别名 | Ro-4995819; Ro4995819; Ro4995819; | ||
| 分子式 | C21H11F6N5 | 分子量 | 447.34 |
| 生物活性 | Decoglurant, also known as Ro 4995819, is a negative allosteric modulator of the mGlu2 and mGlu3 receptors which was under development by Roche for the adjunctive treatment of major depressive disorder. Decoglurant progressed as far as phase II clinical trials but was ultimately discontinued from further development due to disappointing efficacy results. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | mGluR | ||
结构式
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