Dizocilpine
CAS No. | 77086-21-6 | Cat. No. | BCP34654 |
Name | Dizocilpine | ||
Synonyms | MK801; MK 801; MK-801; | ||
Formula | C16H15N | M. Wt | 221.3 |
Description | Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a Kd of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux. | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | AMPA/NMDA |
Structure
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