Dizocilpine

  • Chemical Properties
CAS No. 77086-21-6 Cat. No. BCP34654
Name Dizocilpine
Synonyms MK801; MK 801; MK-801;
Formula C16H15N M. Wt 221.3
  • Biological Activity
Description Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a Kd of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux.
Pathways Ion Channel/Membrane Transporter 
Targets AMPA/NMDA 

Structure

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