SGK3 degrader-1
| CAS No. | 2381320-35-8 | Cat. No. | BCP35166 |
| Name | SGK3 degrader-1 | ||
| Synonyms | PROTAC SGK3 degrader-1;SGK3-PROTAC1; | ||
| Formula | C57H73FN10O11S2 | M. Wt | 1157.38 |
| Description | SGK3 degrader-1 is a potent SGK3 degrader based on PROTAC. PROTAC SGK3 degrader-1 (0.3 μM) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate). | ||
| Pathways | Others Pathway | ||
| Targets | PROTAC | ||
Structure
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