KGA-2727
| CAS No. | 666842-36-0 | Cat. No. | BCP35207 |
| Name | KGA-2727 | ||
| Synonyms | KGA 2727; KGA2727; | ||
| Formula | C26H40N4O8 | M. Wt | 536.62 |
| Description | KGA-2727 is a potent and selective SGLT1 inhibitor for the treatment of diabete. KGA-2727 inhibited SGLT1 potently and highly selectively in an in vitro assay using cells transiently expressing recombinant SGLTs. KGA-2727 inhibited the absorption of glucose but not that of fructose. It has inhibition constant (Ki) values of 97 and 13,600 nM for human (h) SGLT1 and hSGLT2, respectively. | ||
| Pathways | GPCR/G Protein | ||
| Targets | SGLT | ||
Structure
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