Urolithin B
CAS No. | 1139-83-9 | Cat. No. | BCP35736 |
Name | Urolithin B | ||
Synonyms | 3-Hydroxy-6H-benzo[c]chromen-6-one; | ||
Formula | C13H8O3 | M. Wt | 212.2 |
Description | Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass. | ||
Pathways | PI3K/Akt/mTOR MAPK Pathway Epigenetics NFκB | ||
Targets | MEK/ERK NF κB AMPK AKT JNK |
Structure
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