GSK2193874
| CAS No. | 1336960-13-4 | Cat. No. | BCP36070 |
| Name | GSK2193874 | ||
| Synonyms | GSK 2193874; GSK-2193874; GSK2193874A; GSK 2193874A; GSK-2193874A; | ||
| Formula | C37H38BrF3N4O | M. Wt | 691.64 |
| Description | GSK2193874 is a potent antagonist of TRPV4 channels, blocking the influx of calcium induced by the TRPV4 agonist GSK634775 with IC50 values of 2, 5, and 40 nM. It is selective for TRPV4 over ~200 other human receptors, channels, and enzymes. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | TRP Channel | ||
Structure
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