AZD7507
| CAS号 | 1041852-85-0 | 货号 | BCP36143 |
| 中文名 | AZD7507 | ||
| 英文名 | AZD7507 | ||
| 中文别名 | |||
| 英文别名 | AZD-7507; AZD 7507; | ||
| 分子式 | C23H27FN6O3 | 分子量 | 454.51 |
| 生物活性 | AZD7507 is a potent and selective CSF-1R inhibitor (32 nM cell activity), AZD7507 is considered a promising compound as it retained the desired potency and oral pharmacokinetic properties of AZ683. Moreover, in a telemetry study in dogs given a single oral dose, there was no cardiovascular toxicity, no elevation of troponin related to the treatment, and no alteration in the ECG. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | cFMS | ||
结构式
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