Sphingosine 1-phosphate

  • Chemical Properties
CAS No. 26993-30-6 Cat. No. BCP36245
Name Sphingosine 1-phosphate
Synonyms D-erythro-Sphingosine-1-phosphate;C18-Sphingosine 1-phosphate;
Formula C18H38NO5P M. Wt 379.47
  • Biological Activity
Description Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin or other membrane phospholipids.
Pathways GPCR/G Protein 
Targets S1P Receptor 

Structure

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