UNC2025 hydrochloride
| CAS No. | 2070015-17-5 | Cat. No. | BCP36467 |
| Name | UNC2025 hydrochloride | ||
| Synonyms | UNC-2025 hydrochloride; UNC 2025 hydrochloride; UNC2025 HCl; | ||
| Formula | C28H41ClN6O | M. Wt | 513.12 |
| Description | UNC2025 hydrochloride is a potent and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki = 13.3 nM). UNC2025 hydrochloride exhibits an excellent PK properties, and can be used for the investigation of acute leukemia. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FLT3 | ||
Structure
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