KB-0742 hydrochloride
| CAS No. | 2416874-75-2 | Cat. No. | BCP36919 |
| Name | KB-0742 hydrochloride | ||
| Synonyms | KB-0742 hydrochloride;KB-0742 hydrochloride; | ||
| Formula | C16H26ClN5 | M. Wt | 323.87 |
| Description | KB-0742 dihydrochloride is a potent, selective and orally active CDK9 inhibitor against CDK9/cyclin T1 IC50 is 6 nM. KB-0742 dihydrochloride is selective for CDK9/cyclin T1, which is more than 50 times more selective than other CDK kinases. KB-0742 dihydrochloride has potent anti-tumor activity. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | CDK | ||
Structure
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