Ac-YVAD-CMK

  • Chemical Properties
CAS No. 178603-78-6 Cat. No. BCP37297
Name Ac-YVAD-CMK
Synonyms Acetyl-Tyr-Val-Ala-Asp-chloromethylketone;Acetyl-Tyr-Val-Ala-Asp-chloromethylketone;
Formula C24H33ClN4O8 M. Wt 540.99
  • Biological Activity
Description Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1). Ac-YVAD-CMK is neuroprotective in a rat model of cerebral ischemia.
Pathways Protease/Metabolic Enzyme Apoptosis Pathway 
Targets Caspase 

Structure

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