THPP-1

  • Chemical Properties
CAS No. 1257051-63-0 Cat. No. BCP37557
Name THPP-1
Synonyms
Formula C23H21ClN6O3 M. Wt 464.91
  • Biological Activity
Description THPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species.
Pathways Protease/Metabolic Enzyme 
Targets Phosphodiesterase/PDE 

Structure

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