AZ32

  • Chemical Properties
CAS No. 2288709-96-4 Cat. No. BCP37674
Name AZ32
Synonyms AZ-32;AZ 32;
Formula C20H16N4O M. Wt 328.37
  • Biological Activity
Description AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.
Pathways Cell Cycle/DNA Damage PI3K/Akt/mTOR 
Targets ATM/ATR 

Structure

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