6-Nitroveratraldehyde
| CAS No. | 20357-25-9 | Cat. No. | BCP37748 |
| Name | 6-Nitroveratraldehyde | ||
| Synonyms | 4,5-Dimethoxy-2-nitrobenzaldehyde;DMNB;Benzaldehyde, 4,5-dimethoxy-2-nitro-; | ||
| Formula | C9H9NO5 | M. Wt | 211.17 |
| Description | 6-Nitroveratraldehyde is a derivative of vanillin with 100-fold potency compared to vanillin, and acts as an inhibitor of DNA-dependent protein kinase (DNA-PK) (IC50 = 15 μM). DNA-PK is an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells. | ||
| Pathways | Cell Cycle/DNA Damage PI3K/Akt/mTOR | ||
| Targets | DNA PK | ||
Structure
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