4BP-TQS
| CAS No. | 360791-49-7 | Cat. No. | BCP37825 |
| Name | 4BP-TQS | ||
| Synonyms | |||
| Formula | C18H17BrN2O2S | M. Wt | 405.31 |
| Description | 4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs). 4BP-TQS potentiates acetylcholine-induced activation of α7 subunit-containing nAChRs by greater than 540-fold in X. laevis oocytes.1 It activates wild-type α7 subunit-containing nAChRs and nAChRs containing the α7 subunit and W148F, but not M253L, mutations in X. laevis oocytes. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
| Targets | nAChR | ||
Structure
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