ZK-15922
CAS No. | 156965-15-0 | Cat. No. | BCP37860 |
Name | ZK-15922 | ||
Synonyms | ZK159222; ZK159222; | ||
Formula | C32H48O5 | M. Wt | 512.73 |
Description | ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character. | ||
Pathways | Others Pathway | ||
Targets | Vitamin D Related |
Structure
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