ZK-15922

  • Chemical Properties
CAS No. 156965-15-0 Cat. No. BCP37860
Name ZK-15922
Synonyms ZK159222; ZK159222;
Formula C32H48O5 M. Wt 512.73
  • Biological Activity
Description ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character.
Pathways Others Pathway 
Targets Vitamin D Related 

Structure

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