MPS1-IN-3
| CAS号 | 1609584-72-6 | 货号 | BCP37980 |
| 中文名 | MPS1-IN-3 | ||
| 英文名 | MPS1-IN-3 | ||
| 中文别名 | |||
| 英文别名 | Mps1 IN3; Mps1-IN3; | ||
| 分子式 | C26H31N7O4S | 分子量 | 537.64 |
| 生物活性 | MPS1-IN-3 is a selective and potent MPS1 inhibitor with phenotypic consequences similar to those reported for published MPS1 inhibitors such as MPS1-IN-1, MPS1-IN-2, and AZD3146. MPS1-IN-3 sensitizes glioblastoma cells to vincristine both in vitro and in murine tumor models. MPS1 may be a promising therapeutic target for high-grade glioma therapy and that MPS1 inhibition by MPS1-IN-3 efficiently sensitizes glioblastoma cells to antimitotic agents. | ||
| 信号通路 | Cell Cycle/DNA Damage | ||
| 靶 点 | Mps1 | ||
结构式
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