SAR405 R enantiomer
| CAS No. | 1946010-79-2 | Cat. No. | BCP37991 |
| Name | SAR405 R enantiomer | ||
| Synonyms | SAR-405 R enantiomer;SAR 405 R enantiomer; | ||
| Formula | C19H21ClF3N5O2 | M. Wt | 443.85 |
| Description | SAR405 is a potent and selective PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. SAR405 treatment also inhibits autophagy induced either by starvation or by MTOR (mechanistic target of rapamycin) inhibition. Combining SAR405 with everolimus results in a significant synergy on the reduction of cell proliferation using renal tumor cells. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.