Cetrorelix diacetate

  • Chemical Properties
CAS No. 130143-01-0 Cat. No. BCP38364
Name Cetrorelix diacetate
Synonyms Cetrotide acetate;NS-75A; NS75A; NS 75A; D-20761; SB-075 diacetate; SB 075 diacetate; SB075 diacetate;
Formula C70H92N17O14 M. Wt 1551.16
  • Biological Activity
Description Cetrorelix diacetate is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.Cetrorelix is is a gonadotropin-releasing hormone (GnRH) antagonist that is marketed primarily under the brand name Cetrotide. A synthetic decapeptide, it is used is used in assisted reproduction to inhibit premature luteinizing hormone surges. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Pathways GPCR/G Protein 
Targets GnRH Receptor 

Structure

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