Arimoclomol

  • Chemical Properties
CAS No. 289893-25-0 Cat. No. BCP38425
Name Arimoclomol
Synonyms BRX-220; BRX 220; BRX220; BRX-345; BRX 345; BRX345;
Formula C14H20ClN3O3 M. Wt 313.78
  • Biological Activity
Description Arimoclomol is a heat shock protein amplifier, and is potentially useful for the treatment of Niemann-Pick disease type C (NP-C). Arimoclomol is believed to function by stimulating a normal cellular protein repair pathway through the activation of molecular chaperones. Arimoclomol could treat a broad range of diseases. Arimoclomol activates the heat shock response. It is believed to act at Hsp70.
Pathways NFκB 
Targets Keap1 Nrf2 

Structure

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