HIF-2a Translation Inhibitor 76
| CAS No. | 882268-69-1 | Cat. No. | BCP38668 |
| Name | HIF-2a Translation Inhibitor 76 | ||
| Synonyms | |||
| Formula | C9H9N3O4S2 | M. Wt | 287.32 |
| Description | HIF-2a Translation Inhibitor 76 is a cell-permeable HIF-2a translation inhibitor (IC50 value 5 µM). It inhibits HIF-2a translation via enhancing the binding of IRP1 (Iron-Regulatory Protein 1) to the IRE (Iron-Responsive Element) region at the 5' UTR of the HIF-2α mRNA. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | HIF | ||
Structure
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