Pipequaline HCl

  • Chemical Properties
CAS No. 80221-58-5 Cat. No. BCP38837
Name Pipequaline HCl
Synonyms Pipequaline hydrochloride;PK-8165 hydrochloride;
Formula C22H25ClN2 M. Wt 352.91
  • Biological Activity
Description Pipequaline, also known as PK-8165, is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic. Pipequaline acts as a non-selective GABAA receptor partial agonist. While its profile of anxiolytic effects without sedation would appear to have potential medical applications, pipequaline has never been developed for medical use and is currently only used in scientific research.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway 
Targets GABA Receptor 

Structure

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