醋酸氟氢可的松
| CAS号 | 514-36-3 | 货号 | BCP38927 |
| 中文名 | 醋酸氟氢可的松 | ||
| 英文名 | Fludrocortisone acetate | ||
| 中文别名 | |||
| 英文别名 | Fludrocortisone 21-acetate; | ||
| 分子式 | C23H31FO6 | 分子量 | 422.49 |
| 生物活性 | Fludrocortisone Acetate is the acetate salt of a synthetic fluorinated corticosteroid with antiinflammatory and antiallergic activities. As a glucocorticoid-receptor agonist, fludrocortisone binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2 (PLA2). Inhibition of PLA2 activity prevents the release of arachidonic acid, a precursor of eicosanoids such as prostaglandins and leukotrienes; eicosanoids are important mediators in the pro-inflammatory response mechanism. As a mineralocorticoid-receptor agonist, this agent stimulates Na+ reabsorption and water retention and K+ and H+ secretion in the distal tubules and collecting ducts of the kidney. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Glucocorticoid Receptor | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！