Thioperamide

  • Chemical Properties
CAS No. 106243-16-7 Cat. No. BCP39480
Name Thioperamide
Synonyms MR 12842;MR-12842;MR12842;
Formula C15H24N4S M. Wt 292.44
  • Biological Activity
Description Thioperamide is an HRH4 antagonist and selective HRH3 antagonist capable of crossing the blood–brain barrier. Thioperamide negatively regulates the release of histamine and enhances the activity of histaminergic neurons by blocking autoreceptors. Its action on H3 is thought to promote wakefulness and improve memory consolidation.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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