ACH-000143
| CAS No. | 2225836-30-4 | Cat. No. | BCP39663 |
| Name | ACH-000143 | ||
| Synonyms | ACH 000143;ACH000143; | ||
| Formula | C13H16ClN3O3 | M. Wt | 297.74 |
| Description | ACH-000143 is a novel potent melatonin receptor agonist with EC50 of 0.06 nM/0.32 nM against MT1/MT2. ACH-000143 leads to a reduction in body weight gain similar to dapagliflozin with superior results on hepatic steatosis and triglyceride levels in high-fat diet rats. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Melatonin Receptor | ||
Structure
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