Elenbecestat

  • Chemical Properties
CAS No. 1388651-30-6 Cat. No. BCP39709
Name Elenbecestat
Synonyms E2609; E-2609; E 2609;
Formula C19H18F3N5O2S M. Wt 437.44
  • Biological Activity
Description Elenbecestat is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Aβ peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Aβ levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.
Pathways Neuro Signaling Pathway 
Targets Beta secretase 

Structure

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