Elenbecestat
CAS号 | 1388651-30-6 | 货号 | BCP39709 |
中文名 | Elenbecestat | ||
英文名 | Elenbecestat | ||
中文别名 | |||
英文别名 | E2609; E-2609; E 2609; | ||
分子式 | C19H18F3N5O2S | 分子量 | 437.44 |
生物活性 | Elenbecestat is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Aβ peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Aβ levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD. | ||
信号通路 | Neuro Signaling Pathway | ||
靶 点 | Beta secretase |
结构式
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