Venlafaxine

  • Chemical Properties
CAS No. 93413-69-5 Cat. No. BCP39881
Name Venlafaxine
Synonyms Wy-45030; Wy45030; Wy 45030;
Formula C17H27NO2 M. Wt 277.4
  • Biological Activity
Description Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases.
Pathways Neuro Signaling Pathway 
Targets SSRI 

Structure

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