文拉法辛
| CAS号 | 93413-69-5 | 货号 | BCP39881 |
| 中文名 | 文拉法辛 | ||
| 英文名 | Venlafaxine | ||
| 中文别名 | |||
| 英文别名 | Wy-45030; Wy45030; Wy 45030; | ||
| 分子式 | C17H27NO2 | 分子量 | 277.4 |
| 生物活性 | Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases. | ||
| 信号通路 | Neuro Signaling Pathway | ||
| 靶 点 | SSRI | ||
结构式
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