NF-κB-IN-1

  • Chemical Properties
CAS No. 1227098-15-8 Cat. No. BCP40303
Name NF-κB-IN-1
Synonyms
Formula C31H30O8 M. Wt 530.57
  • Biological Activity
Description NF-κB-IN-1, a 4-arylidene crucumin analogue, is a potent NF-κB signaling pathway inhibitor. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.
Pathways NFκB 
Targets IκB/IKK 

Structure

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