MRK-016
CAS No. | 342652-67-9 | Cat. No. | BCP40367 |
Name | MRK-016 | ||
Synonyms | MRK 016;MRK016; | ||
Formula | C17H20N8O2 | M. Wt | 368.39 |
Description | MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator with EC50 value of 3 nM. It has nootropic properties. MRK-016 can produce rapid, ketamine-like antidepressant effects in animal models of depression. | ||
Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
Targets | GABA Receptor |
Structure
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