氯米芬
| CAS号 | 911-45-5 | 货号 | BCP40562 |
| 中文名 | 氯米芬 | ||
| 英文名 | Clomifene | ||
| 中文别名 | |||
| 英文别名 | Clomiphene; | ||
| 分子式 | C26H28ClNO | 分子量 | 405.96 |
| 生物活性 | Clomifene is a selective estrogen receptor modulator (SERM) that has become the most widely prescribed drug for ovulation induction to reverse anovulation or oligoovulation. Clomiphene is a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. | ||
| 信号通路 | Hormone Pathay | ||
| 靶 点 | Estrogen Receptor | ||
结构式
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